Prenatal screening above aneuploidies that is Pre-Eclampsia

Application of proteomics to prenatal screening and diagnosis for aneuploidies.

Current screening for fetal aneuploidies relies on biochemical and ultrasound measurements, and the sensitivity and specificity needs to be improved to reduce the number of pregnant women subjected to invasive diagnostic procedures, such as amniocentesis. Proteomic technologies enable new strategies for discovering biomarkers from complex biological fluids in a high-throughput and sensitive man...

Economic assessment of screening for pre-eclampsia.

BACKGROUND Pre-eclampsia is a major contributor to maternal and neonatal morbidity and mortality. Our objectives in this study are to economically assess, from the payer perspective, routine screening for pre-eclampsia using placental markers -placental protein 13 and placental growth factor - and uterine artery Doppler compared with standard care. METHODS A decision model was developed, whic...

Eclampsia Precedes Pre-Eclampsia

Eclampsia is an extremely severe form of preeclampsia characterized by the sudden onset of generalized tonic clonic seizures. It may occur quite abruptly, without any warning manifestations. This is a case report where Mrs.X was normotensive throughout her pregnancy who underwent emergency cesarean section for cephalo pelvic disproportion and threw generalized tonic clonic seizures on the first...

Is apoptosis cause of pre-eclampsia?

Pre-eclampsia is the main cause of fetal and maternal morbidity and death associated with hypertension during complicating pregnancy. During physiological pregnancy, the immunological system undergoes secondary modifications, with an "exchange" between mother and fetus. Cytokines play an important role in the complex condition of partial fetal "rejection". It has suggested that the condition de...

Prevention of pre-eclampsia--is it possible?